I think you are over thinking this. Its not a Saturn booster rocket or the space shuttle. Its just a bunch of boxes/rectangles, Probably made out of 3/4" lumber and/or 3/4" plywood with a face frame and 1/4" plywood back.
If you dado in some of the shelves in to the sides it will really firm the 'box' up. If the shelves are about 36" wide or less and made out of 3/4" solid lumber they won't sag unless you put a couple of hundred pounds of books on the one shelf. Put a 1-1/4" thick front strip on the shelf and it will hold even more.
The whole cabinet will typically hold whatever the floor will hold. The floor will hold more than anyone could practically put in the cabinet.
Here is the design for one I did
http://i180.photobucket.com/albums/x168/DJDphotos/04170001.jpg
for this cabinet
http://i180.photobucket.com/albums/x168/DJDphotos/09040001a.jpg
here is it loaded up
http://i180.photobucket.com/albums/x168/DJDphotos/10300009.jpg
The biggest challenge was how to go about making it in pieces and merely 'assembling' it in the house that was 10 miles from the shop. When done it looks like it was custom made in place one stick/board at a time. The other challenge is that some of those 'cubicles' are actually recessed in to the wall another 4" to gain depth for the stereo equipment. The existing lights in the ceiling limited how deep the cabinet come out in to the room.
Granted, if you want looooong shelves and minimal lumber thickness, or if you just want to nail it together with no rabbits/dados/etc, then it might have to be 'engineered'.