Most definitely - two 1/8", two 1/4". My bench top drill press doesn't have a wide enough throat to drill the very middle inside entry holes, so I had to cut the perimeter before I finished the inside. My pistol grip dremel drill didn't have enough oomph to power a bit through the layers. I just need to cut backers now.
I think there were only around 250 holes I drilled but it's difficult to keep count. Took about 12 hours to cut, and an absurd number of blades (I don't think I have ever broken more blades! I did load multiple clamps for this one so I didn't waste as much time changing them out - that was kind of cool)
