Use them anywhere you like except drywall. Too expensive for drywall. Really great screws
I’ve actually been having issues with them recently. I built some lumber storage racks and cabinet for my miter saw and they kept spinning out when the head got to the side of the panels. I predrilled and counter sunk but could not get them to suck in any farther. I got the same size PowerPros from Lowe’s and they worked great. I tried adjusting predrill diameter sizes but just couldn’t get them to tighten up no matter what I did. I used to only use Spax for general work but the last 3 or 4 boxes I’ve gotten have not worked well at all.
I've also considered trying some not from home depot to see if they're better
I bet the reason they spin out on you may be that the threads near the tip are smaller than up near the head, more so than most screws. This along with the serrated "teeth" near the tip makes them easy to drill them in without a pilot hole. Therefore you might need a little longer screw if possible. Just a theory or guess on my part and not researched or measured.